Sildalist is a powerful oral medication used to treat erectile dysfunction (ED) and sometimes premature ejaculation in men. What sets Sildalist apart from other ED medications is that it contains a unique combination of two active ingredients: Sildenafil Citrate and Tadalafil. Typically, it is taken 30 to 60 minutes before sexual activity, and like other ED drugs, it only works with sexual stimulation. Sildalist should be taken once per day maximum, and not combined with alcohol, grapefruit juice, or nitrate medications due to the risk of serious side effects such as sudden blood pressure drops.