The global health community faces a serious threat from cardiovascular disease. Important discoveries from heart research are still not applied in clinical practice, despite advancements in understanding the cellular and molecular features of heart failure and lowering its death rates. Information regarding the effects of molecular targets in the system, as well as experimental systems that include whole, multicellular tissue components and external manipulation for disease modeling and treatment simulation, are necessary for the effective translation of fundamental biomedical research.
PCHS is being used more and more to test new medications and biochemical products. PCHS provides a high-throughput and pertinent model for drug discovery by maintaining the structural and functional integrity of human or animal organs, yielding precise phenotypic data.
More details: Precision-Cut Heart Slice Model Introduction
