PBC (Primary Biliary Cholangitis), a life-long condition, develops as a result of step-by-step processes until liver damage manifests, but diagnosis sometimes remains undetected. The disease is associated with widespread false views, and it is low on visibility which in turn slows the diagnostic process and proper management.
Bile ducts in primary biliary cirrhosis are damaged by chronic autoimmune inflammation, which leads to the loss of liver functionality. Bile, a bile and a liver-derived excretory of toxic substances from body fluids, is mainly responsible for fat digestion. When these pipes are damaged, toxic substances accumulate in the liver, which causes inflammation. Later, the patient develops cirrhosis and ends up with liver failure.