Yes, Can Smoking Weed Everyday Cause Erectile Dysfunction over time, although the effects may vary depending on the individual and other factors like frequency, dose, and overall health. Daily marijuana use, especially in large amounts, can contribute to erectile dysfunction through its effects on blood flow, hormones, psychological well-being, and overall sexual function. However, the extent to which cannabis affects ED can vary depending on the individual. If you’re concerned about the impact of cannabis on your sexual health, it might be worth reducing or stopping use and discussing your symptoms with a healthcare provider.