Hyperphosphatemia, a condition where the phosphate levels in the blood are abnormally elevated, can occur on a frequent basis, especially among the people who have chronic kidney disease. If it progresses unhindered it can involve different illnesses such as heart disease and hardening of tissues. Hyperphosphatemia manifested as an abnormally high phosphate level in your blood (between 2.5 and 4.5 mg/dL.), can be the consequence of a number of pathological conditions. It is often found in people with kidney disorders where the kidneys are the sites of reduced phosphorus excretion. As a result, the excess phosphate builds up in the blood. The excess amount of accumulated phosphate can interfere and may have harmful effects.